Annotated protein: | Glycine receptor subunit alpha-1 (Glycine receptor 48 kDa subunit) (Glycine receptor strychnine-binding subunit). Gene symbol: GLRA1. Taxonomy: Rattus norvegicus (Rat). Uniprot ID: P07727 |
antibody wiki: | |
SynGO gene info: | SynGO data @ GLRA1 |
Ontology domain: | Cellular Component |
SynGO term: | integral component of presynaptic membrane (GO:0099056) |
Synapse type(s): | Calyx of Held |
Annotated paper: | Hruskova B, et al. "Differential distribution of glycine receptor subtypes at the rat calyx of Held synapse" J Neurosci. 2012 Nov 21;32(47):17012-24 PMID:23175852 |
Figure(s): | fig.8C |
Annotation description: | Glycine Alpha 1 subunit, detected presynaptically in Calyx with immuno EM. 8/9/2017 Pim - Based on the known transmembrane topology of the protein, the "integral component of ... membrane" term was chosen |
Evidence tracking, Biological System: | Intact tissue |
Evidence tracking, Protein Targeting: | Antibody (detection) |
Evidence tracking, Experiment Assay: | Electron Microscopy |
Annotator(s): | Niels Cornelisse (ORCID:0000-0001-9425-2935) Matthijs Verhage (ORCID:0000-0002-2514-0216) |
Lab: | Department of Functional Genomics, Center for Neurogenomics and Cognitive Research, Vrije Universiteit Amsterdam, 1081 HV Amsterdam, The Netherlands |
SynGO annotation ID: | 1192 |
Dataset release (version): | 20231201 |
View annotation as GO-CAM model: |