Annotated protein:GRIP1-associated protein 1 (GRASP-1) [Cleaved into: GRASP-1 C-terminal chain (30kDa C-terminus form)]. Gene symbol: GRIPAP1. Taxonomy: Rattus norvegicus (Rat). Uniprot ID: Q9JHZ4
antibody wiki:
SynGO gene info:SynGO data @ GRIPAP1
Ontology domain:Biological Process
SynGO term:regulation of neurotransmitter receptor transport, endosome to postsynaptic membrane (GO:0099152)
Synapse type(s):hippocampus, glutamatergic
Annotated paper:Hoogenraad CC, et al. "Neuron specific Rab4 effector GRASP-1 coordinates membrane specialization and maturation of recycling endosomes" PLoS Biol. 2010 Jan 19;8(1):e1000283 PMID:20098723
Figure(s):figure 6
Annotation description:The data in figure 6 shows the effect of GRASP-1 (GRIPAP1) in regulating the recycling of AMPARs from RER to plasma membrane.
Evidence tracking, Biological System:Cultured neurons
Evidence tracking, Protein Targeting:RNAi / shRNA
Evidence tracking, Experiment Assay:Confocal
Annotator(s):Harold MacGillavry (ORCID:0000-0002-6153-3586)
Casper Hoogenraad (ORCID:0000-0002-2666-0758)
Lab:Department of Biology, Faculty of Science, Utrecht University, 3584 CH Utrecht, The Netherlands
SynGO annotation ID:1190
Dataset release (version):20231201
View annotation as GO-CAM model:Gene Ontology