| Annotated protein: | GRIP1-associated protein 1 (GRASP-1) [Cleaved into: GRASP-1 C-terminal chain (30kDa C-terminus form)]. Gene symbol: GRIPAP1. Taxonomy: Rattus norvegicus (Rat). Uniprot ID: Q9JHZ4 |
| antibody wiki: | |
| SynGO gene info: | SynGO data @ GRIPAP1 |
| Ontology domain: | Biological Process |
| SynGO term: | regulation of recycling endosome localization within postsynapse (GO:0099158) |
| Synapse type(s): | hippocampus, glutamatergic |
| Annotated paper: | Hoogenraad CC, et al. "Neuron specific Rab4 effector GRASP-1 coordinates membrane specialization and maturation of recycling endosomes" PLoS Biol. 2010 Jan 19;8(1):e1000283 PMID:20098723 |
| Figure(s): | figure 5F-H |
| Annotation description: | The data in figure 5 shows the involvement of GRASP-1 (GRIPAP1) in the transport of postsynaptic RER into the spine. |
| Evidence tracking, Biological System: | Cultured neurons |
| Evidence tracking, Protein Targeting: | RNAi / shRNA |
| Evidence tracking, Experiment Assay: | Confocal |
| Annotator(s): | Harold MacGillavry (ORCID:0000-0002-6153-3586) Casper Hoogenraad (ORCID:0000-0002-2666-0758) |
| Lab: | Department of Biology, Faculty of Science, Utrecht University, 3584 CH Utrecht, The Netherlands |
| SynGO annotation ID: | 1189 |
| Dataset release (version): | 20231201 |
| View annotation as GO-CAM model: |  |