| Annotated protein: | Eps-15 protein (SD09478p). Gene symbol: EPS-15. Taxonomy: Drosophila melanogaster (Fruit fly). Uniprot ID: Q8WQ61 |
| antibody wiki: | |
| SynGO gene info: | SynGO data @ EPS15 SynGO data @ EPS15L1 |
| Ontology domain: | Biological Process |
| SynGO term: | synaptic vesicle endocytosis (GO:0048488) |
| Synapse type(s): | Neuro-muscular junction |
| Annotated paper: | Koh TW, et al. "Eps15 and Dap160 control synaptic vesicle membrane retrieval and synapse development" J Cell Biol. 2007 Jul 16;178(2):309-22 PMID:17620409 |
| Figure(s): | fig 6 |
| Annotation description: | In figure 6 they use FM1-43 dye uptake experiments to demonstrate defects in synaptic vesicle endocytosis in Eps15 null flies. |
| Evidence tracking, Biological System: | Intact tissue |
| Evidence tracking, Protein Targeting: | Genetic transformation (eg; knockout, knockin, mutations) |
| Evidence tracking, Experiment Assay: | Optical physiology |
| Annotator(s): | Peter McPherson (ORCID:0000-0001-7806-5662) |
| Lab: | Department of Neurology and Neurosurgery, Montreal Neurological Institute, McGill University, Montreal, QC H3A 2B4, Canada |
| SynGO annotation ID: | 1176 |
| Dataset release (version): | 20231201 |
| View annotation as GO-CAM model: |  |