Annotated protein: | Metabotropic glutamate receptor 7 (mGluR7). Gene symbol: GRM7. Taxonomy: Rattus norvegicus (Rat). Uniprot ID: P35400 |
antibody wiki: | |
SynGO gene info: | SynGO data @ GRM7 |
Ontology domain: | Cellular Component |
SynGO term: | integral component of presynaptic active zone membrane (GO:0099059) |
Synapse type(s): | cerebral cortex, GABAergic cerebral cortex, glutamatergic |
Annotated paper: | Dalezios Y, et al. "Enrichment of mGluR7a in the presynaptic active zones of GABAergic and non-GABAergic terminals on interneurons in the rat somatosensory cortex" Cereb Cortex. 2002 Sep;12(9):961-74 PMID:12183395 |
Figure(s): | Fig. 1A, C-D, Fig. 2, Fig. 3 |
Annotation description: | Kainate GluR7 (Grik 3) receptor 8/9/2017 Pim - Based on the known transmembrane topology of the protein, the "integral component of ... membrane" term was chosen. |
Evidence tracking, Biological System: | Intact tissue |
Evidence tracking, Protein Targeting: | Antibody (detection) |
Evidence tracking, Experiment Assay: | Electron Microscopy |
Annotator(s): | Niels Cornelisse (ORCID:0000-0001-9425-2935) Matthijs Verhage (ORCID:0000-0002-2514-0216) |
Lab: | Department of Functional Genomics, Center for Neurogenomics and Cognitive Research, Vrije Universiteit Amsterdam, 1081 HV Amsterdam, The Netherlands |
SynGO annotation ID: | 1119 |
Dataset release (version): | 20231201 |
View annotation as GO-CAM model: |