Annotated protein: | Glutamate receptor ionotropic, kainate 1 (GluK1) (Glutamate receptor 5) (GluR-5) (GluR5). Gene symbol: GRIK1. Taxonomy: Rattus norvegicus (Rat). Uniprot ID: P22756 |
antibody wiki: | |
SynGO gene info: | SynGO data @ GRIK1 |
Ontology domain: | Cellular Component |
SynGO term: | integral component of presynaptic membrane (GO:0099056) |
Synapse type(s): | dorsal root ganglion (DRG), glutamatergic |
Annotated paper: | Lucifora S, et al. "Presynaptic low- and high-affinity kainate receptors in nociceptive spinal afferents" Pain. 2006 Jan;120(1-2):97-105 PMID:16360275 |
Figure(s): | figure 2A |
Annotation description: | Immuno EM in afferent terminals of rat DRG. 8/9/2017 Pim - Based on the known transmembrane topology of the protein, the "integral component of ... membrane" term was chosen. - Afferent input into DRG is known to be glutamatergic |
Evidence tracking, Biological System: | Intact tissue |
Evidence tracking, Protein Targeting: | Antibody (detection) |
Evidence tracking, Experiment Assay: | Electron Microscopy |
Annotator(s): | Niels Cornelisse (ORCID:0000-0001-9425-2935) Matthijs Verhage (ORCID:0000-0002-2514-0216) |
Lab: | Department of Functional Genomics, Center for Neurogenomics and Cognitive Research, Vrije Universiteit Amsterdam, 1081 HV Amsterdam, The Netherlands |
SynGO annotation ID: | 1114 |
Dataset release (version): | 20231201 |
View annotation as GO-CAM model: |