| Annotated protein: | Septin-7 (CDC10 protein homolog). Gene symbol: SEPTIN7. Taxonomy: Mus musculus (Mouse). Uniprot ID: O55131 |
| antibody wiki: | |
| SynGO gene info: | SynGO data @ SEPTIN7 |
| Ontology domain: | Cellular Component |
| SynGO term: | presynaptic membrane (GO:0042734) |
| Synapse type(s): | cerebellum hippocampus |
| Annotated paper: | Kinoshita A, et al. "Differential localization of septins in the mouse brain" J Comp Neurol. 2000 Dec 11;428(2):223-39 PMID:11064363 |
| Figure(s): | Fig 6 |
| Annotation description: | Fig6: CDC10 (SEPT7) in cerebellum, clear labeling of DAB in presynapse (Fig6A), and synaptic terminal plasma membrane in CA3 hippocampus (Fig6C). No quantification is offered. 10/10/2017 Pim - The authors state in Fig.6 "DAB deposition for CDC10 is localized in the presynaptic axon terminals in the granule cell layer. The tips of the axon terminal membrane, rather than around the vesicles, are densely labeled for CDC10." |
| Evidence tracking, Biological System: | Intact tissue |
| Evidence tracking, Protein Targeting: | Antibody (detection) |
| Evidence tracking, Experiment Assay: | Electron Microscopy |
| Annotator(s): | Jan van Weering (ORCID:0000-0001-5259-4945) Matthijs Verhage (ORCID:0000-0002-2514-0216) |
| Lab: | Department of Functional Genomics, Center for Neurogenomics and Cognitive Research, Vrije Universiteit Amsterdam, 1081 HV Amsterdam, The Netherlands |
| SynGO annotation ID: | 1028 |
| Dataset release (version): | 20231201 |
| View annotation as GO-CAM model: |  |